What causes HMB?

What causes HMB?

Although there are several different causes of HMB, in about half of cases no underlying reason can be identified⁹.

Underlying conditions that can cause HMB⁹

Gynaecological conditions: Uterine fibroids Endometrial polyps Endometriosis and adenomyosis Polycystic ovary syndrome Pelvic inflammatory disease	Coagulation disorders Von Willebrand disease	Other systemic conditions Hypothyroidism  Diabetes mellitus  Hyperprolactinaemia  Hepatic disease  Renal disease	Cancer Of the cervix, uterus, or endometrium

Pharmacists should also be aware that certain medications can also cause HMB⁹:

• Anticoagulants
• Antiplatelet drugs
• Herbal supplements, e.g. gingko, ginseng, soya
• Intra-uterine contraceptive devices (sometimes known as the copper coil)
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Oral contraceptives
• Selective serotonin reuptake inhibitors.